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'MEAT' THE CULPRIT
Many food-borne human illnesses are
related to the eating of dead animals.

Medical mystery solved in the slaughterhouse
A. Chris Gajilan

AUSTIN, Minnesota (Feb. 28) -- A mysterious nerve disorder that hit some slaughterhouse employees with debilitating symptoms apparently was caused by inhaling a fine mist of pig brain tissue.

While eating pig brains isn't dangerous, inhaling fumes from particles of pig brain matter can be, scientists say.

A translator assisting Spanish-speaking patients helped to expose the hidden risk, which prompted the Centers for Disease Control and Prevention to name a new disease and led to changes in how pig brains are harvested.

Susan Kruse is one of the patients who suffered from the disease that's called progressive inflammatory neuropathy, or PIN.

Her quest for health started with bizarre, unexplainable symptoms and took her to nearly 20 doctors.

For more than 15 years, the 37-year-old mother worked a regular shift at Quality Pork Processors, QPP, in Austin, Minnesota. In her spare time, she renovated her home with her boyfriend, son and stepdaughter.

In November 2006, the symptoms began. First, there were charley horse cramps in her left calf that wouldn't go away. Within days, the debilitating aches moved to her right leg. Within weeks, the tips of her fingers began to go numb.

Soon, the pins and needles spread to her feet.

She couldn't figure out what was happening to her body. She wasn't doing anything differently. She hadn't had any major health problems in the past.

Kruse went to local doctors, but they had never seen anything quite like it.
"I was very scared," she said.

She underwent countless tests and saw almost 20 doctors, but all the diagnoses were hazy -- everything from depression to gallstones.

By February 2007, Kruse could no longer stand for long periods. She had to give up her job at a pork processing plant.

"The doctors couldn't believe how fast it came on. In a four-month period I went from being able to walk to not being able to walk," Kruse said. "I'm only in my middle 30s -- who needs to be in a wheelchair in the middle 30s?"

While Kruse continued to struggle with her illness, something strange was unfolding a few blocks from her home.

At Austin Medical Center, a language interpreter began to notice a pattern.

Over the course of 2007, she found herself translating a similar list of ailments from Spanish-speaking patients to doctors.

She heard the same complaints over and over: aching leg pain; an odd numbness and tingling in the hands, legs and sometimes face; weakness; tiredness.

"There was a group of patients seeing different doctors that all seemed to have a similar set of complaints," said Dr. Daniel Lachance, a neurologist.

At the time, Lachance worked at the Austin Medical Center and the Mayo Clinic in Rochester. He asked Austin doctors to try to refer all the similar cases to him.

By late 2007, his team tracked down 12 people, including Kruse, with similar stories.

"These individuals, one, had a common pattern of illness, but also they had something else in common," Lachance said. "They all appeared to work in the same place, which is Quality Pork Processors in Austin."

But the similarities didn't end there.

"When we looked a little further, it seemed that these workers were clustered in a particular part of the plant," according to Dr. Ruth Lynfield, a leading epidemiologist at the Minnesota Department of Health.

Lynfield surveyed the plant with QPP President Kelly Wadding. They focused on a section of the plant called the "head table," the area where brain tissue was harvested and packaged for export.

The market for pig brain tissue includes the American South, where it's used in dishes such as brains and eggs. It's also sold in some Asian countries, such as Cambodia and China, for various recipes, including stir-fries and stews. The brain tissue processed at QPP was used mainly for export to Asia.

State and federal health authorities have said eating pork brains is safe. It's the harvesting method, called "blowing brains," that posed the health risk.

In the procedure, high blasts of compressed air were shot into the head cavity to remove the brains. Sometimes the liquid combined with brain tissue and turned into a mist.

Health investigators said droplets of the mist could have entered a worker's system through the mucous membranes in the nose or mouth. Once in the body, the foreign pig brain matter prompted the immune system to produce antibodies to attack it, in a process similar to an allergic reaction.

But the foreign matter seems to have also triggered an attack on the body's nerve tissue, killing some of the nerves and causing the mysterious numbness.

On January 31, the CDC gave a new name to the unique constellation of ailments: progressive inflammatory neuropathy, or PIN.

"The pattern of abnormalities falls into a combination that we really have not seen with other illnesses," Lachance said.

He is helping to investigate whether PIN cases went unreported or undetected before late 2006.

The CDC also is tracking two other plants that used the procedure. At one plant in Indiana, there have been three confirmed cases. There have been no cases confirmed at a Nebraska plant.

Pig brains are no longer harvested with compressed air. Health authorities have said swift action by QPP management were key to containing the outbreak.

Wadding, who has been QPP president since 1997, said, "Since we put in some precautionary measures and stopped harvesting brains, we have not had any new cases."

To date, no one has died and most patients have recovered and returned to work.

Kruse remains unable to work, but she said she has felt some relief with immunotherapy treatments and medications.

While health authorities are convinced the outbreak is contained, they said it will take months, perhaps years, to understand fully what caused or triggered the illness in workers. --

The Cutting Edge
Which Cut Is Older?
(It's a Trick Question)

By Marian Burros

If some of the meat in supermarkets is looking rosier than it used to, the reason is that a growing number of markets are selling it in airtight packages treated with a touch of carbon monoxide to help the product stay red for weeks.

Both of these steaks were red when bought on February, 3. Kept refrigerated, they were then photographed on February, 16. Why the difference? The one at top was treated with a process that has some consumer groups angered.

This form of "modified atmosphere packaging," a technique in which other gases replace oxygen, has become more widely used as supermarkets eliminate their butchers and buy precut, "case-ready" meat from processing plants.

The reason for its popularity in the industry is clear. One study, conducted at Oklahoma State University for the Cattlemen's Beef Board in 2003, said retailers lost at least $1 billion a year as meat turned brown from exposure to oxygen, because, though it might still be fairly fresh and perfectly safe, consumers simply judged meat's freshness by its color.

The carbon monoxide is itself harmless at the levels being used in the treated packaging. But opponents say that the process, which is also used to keep tuna rosy, allows stores to sell meat that is no longer fresh, and that consumers would not know until they opened the package at home and smelled it. Labels do not note whether meat has been laced with carbon monoxide.

The Food and Drug Administration approved use of the process in 2004. The Washington Post reported in its Monday editions that Kalsec, a Michigan producer of a natural food extract that helps slow the discoloring of the meat but does not "fix" it in the same way as carbon monoxide, had petitioned the agency to reverse that decision.

The Consumer Federation of America and the advocacy group Safe Tables Our Priority have written a letter to the agency in support of the petition because, they say, the bright red color could mask spoilage and dangerous bacteria in older meat or meat that has not been kept at the proper temperature.

Supermarket chains including A.&P. and Pathmark do not carry the treated meat, but it is showing up with increasing frequency elsewhere. In New York City, it is sold at 30 Gristede's stores, at D'Agostino markets under the labels Laura's Lean Beef and Creekstone's, and at the Morton Williams stores in the Associated chain. A spokeswoman for Safeway did not respond to phone calls and e-mail messages about sale of the treated meat there, but it was available at a Safeway market in Bethesda, Md., earlier this month. SuperTarget stores are also selling it, and Wal-Mart reports carrying it in 150 stores.

"This is what is going to happen in the meat business," said John A. Catsimatidis, chairman and chief executive of Gristede's. "The meat looks great. It looks as red as the day it was cut."

Processors say treated ground meat can be sold for 28 days after leaving the plant, and solid cuts for 35 days. The agribusiness company Cargill says it has sold 100 million packages in the last year.

Randy Huffman of the American Meat Institute Foundation, an industry group, said, "The primary benefit in providing this product to consumers is the red color they have grown to expect."

In a firsthand look at the treated meat, a package of a conventionally wrapped rib steak and one with the carbon monoxide were both red when bought on Feb. 3 near Washington. They were then kept refrigerated. By Feb. 16, when they were photographed for the pictures that appear with this article, the conventional meat was brown, but the treated meat was still rosy. And as of yesterday, other treated meat bought at the same time was still red despite having been left unrefrigerated on a kitchen counter since Feb. 14.

Some food scientists who approve of other forms of modified atmosphere packaging as a way of extending a product's life say this form of it can be unsafe. Michael Doyle, director of the Center for Food Safety at the University of Georgia, says one study found that when meat in modified packages that included carbon monoxide was stored at 10 degrees above the proper temperature, salmonella grew more easily.

Representative John D. Dingell of Michigan, the ranking Democrat on the House Energy and Commerce Committee, has asked the F.D.A. to explain its approval of the process.

"It's just common sense that when consumers buy meat, they use color as an important indicator of its freshness," Mr. Dingell said in an e-mail message to a reporter. "For F.D.A. to rely on a promise of some stamp on the package that says 'use or freeze by' is just naïve." See I Do Not Eat Dead Animals. --


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  *Consultation with a health care professional should occur before applying adjustments or treatments to the body, consuming medications or nutritional supplements and before dieting, fasting or exercising. None of these activities are herein presented as substitutes for competent medical treatment.

 

 

 

 

 

 

 

 

 

 

 

 

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